[Kris L. Christine]

CANINE RABIES VACCINE CHALLENGE STUDIES BEGIN !

One of the most important vaccine research studies in veterinary medicine is underway at the University of Wisconsin School of Veterinary Medicine in Madison. Dr. Ronald Schultz, a leading authority on veterinary vaccines and Chair of the Department of Pathobiological Sciences, has begun concurrent 5 and 7 year challenge studies to determine the long-term duration of immunity of the canine rabies vaccine, with the goal of extending the state-mandated interval for boosters. These will be the first long-term challenge studies on the canine rabies vaccine to be published in the United States.

Dr. Schultz comments that: "We are all very excited to start this study that will hopefully demonstrate that rabies vaccines can provide a minimum of 7 years of immunity."

This research is being financed by The Rabies Challenge Fund, a charitable trust founded by pet vaccine disclosure advocate Kris L. Christine of Maine, who serves as Co-Trustee with world-renowned veterinary research scientist and practicing clinician, Dr. W. Jean Dodds of Hemopet in California. The Rabies Challenge Fund recently met its goal of $177,000 to fund the studies’ first year budget with contributions from dog owners, canine groups, trainers, veterinarians, and small businesses. Annual budget goals of $150,000 for the studies must be met in the future.

Dr. Jean Dodds, DVM states: "This is the first time in my 43 years of involvement in veterinary issues that what started as a grass-roots effort to change an outmoded regulation affecting animals will be addressed scientifically by an acknowledged expert to benefit all canines in the future."

Scientific data published in 1992 by Michel Aubert and his research team demonstrated that dogs were immune to a rabies challenge 5 years after vaccination, while Dr. Schultz’s serological studies documented antibody titer counts at levels known to confer immunity to rabies 7 years post-vaccination. This data strongly suggests that state laws requiring annual or triennial rabies boosters for dogs are redundant. Because the rabies vaccine is the most potent of the veterinary vaccines and associated with significant adverse reactions, it should not be given more often than is necessary to maintain immunity. Adverse reactions such autoimmune diseases affecting the thyroid, joints, blood, eyes, skin, kidney, liver, bowel and central nervous system; anaphylactic shock; aggression; seizures; epilepsy; and fibrosarcomas at injection sites are linked to rabies vaccinations.

Study co-trustee Kris Christine adds: “Because the USDA does not require vaccine manufacturers to provide long-term duration of immunity studies documenting maximum effectiveness when licensing their products, concerned dog owners have contributed the money to fund this research themselves. We want to ensure that rabies immunization laws are based upon independent, long-term scientific data.”

More information and regular updates on The Rabies Challenge Fund and the concurrent 5 and 7 year challenge studies it is financing can be found at the fund’s website designed by volunteer Andrea Brin at: funds raised to date.

PERMISSION GRANTED TO POST AND CROSS-POST THIS MESSAGE If you wish to be added to my e-mail list for updates on the Rabies Challenge Fund, please contact me at ledgespring@lincoln.midcoast.com .

If anyone would like copies of the American Animal Hospital Association's Canine Vaccine Guidelines, the 1992 French challenge study demonstrating that dogs were immune to a rabies challenge 5 years after vaccination, the 2003 Italian study documenting fibrosarcomas at the presumed injection sites of rabies vaccines in dogs, as well as Dr. W. Jean Dodds' papers on vaccinal adverse reactions, please e-mail me at ledgespring@lincoln.midcoast.com.

Duration of Immunity to Canine Vaccines: What We Know and Don't Know, Dr. Ronald Schultz Duration of Immunity

World Small Animal Veterinary Association 2007 Vaccine Guidelines - WSAVA - Scientific Advisory Committee Scroll down to Vaccine Guidelines 2007 (PDF)

The 2003 American Animal Hospital Association's Canine Vaccine Guidelines are accessible online at Special Report .

The 2006 American Animal Hospital Association's Canine Vaccine Guidelines are downloadable in PDF format at About AAHA .

Veterinarian, Dr. Robert Rogers,has an excellent presentation on veterinary vaccines at Home

HelpingAnimals.com // KP'S DOG BLOG // When the Ends Don't Justify the Means
This is really outrageous. As many of you know, I despise the fact that rabies vaccinations are required for dogs every three years and even annually in some states. I've read about all the adverse reactions and the belief of many holistic vets that rabies vaccinations confer immunity for a lifetime. Nobody would like to see the laws changed to allow dogs to be vaccinated for rabies less frequently more than I would. However, I draw the line at torturing animals in order to accomplish that.
Apparently, some people have no such scruples, such as two people whom I admired and respected up until recently, when I read the "Rabies Challenge Fund Charitable Trust Research Study" for which one of them is fundraising and the other is the principal investigator. In this study, two rather large groups of beagles (each with at least 35 members―it's not known exactly how many) will be isolated for five years or seven years, depending on the group; at least 25 of them will be vaccinated; and then they will all be injected with rabies virus to see who dies and who doesn't. The man doing the experiment is Ronald Schultz, D.V.M., chair of pathobiology at the University of Wisconsin School of Veterinary Medicine and an outspoken critic of the laws regarding rabies vaccinations, and the person raising the funds for the experiment is none other than W. Jean Dodds, D.V.M., a veteran of the holistic veterinary medical community. I find this terribly disturbing and hypocritical.

Death by rabies is ugly indeed. The virus infects the brain, causing encephalitis, and can also attack the spinal cord. There can be everything from fever and flu-like symptoms to anxiety, confusion, erratic behavior, aggression, disorientation, seizures, partial paralysis, coma, and death from respiratory arrest. One of the horrible aspects of the disease is that the jaw and throat become paralyzed, making it impossible to drink or even swallow one's own saliva, causing the characteristic drooling.
Of course, none of this is mentioned in Dodds' fundraising. I doubt that she would get a dime if it were. She is soliciting funds from dog lovers of all kinds, preying on their fears for their own dogs' health while totally misleading them. Her Web site and her flier contain not a single word about the negative aspects and gruesome details of the actual experiment. This is deceitful at best. The idea of torturing upwards of 70 dogs in order to improve the health of the rest of the dog population is no different from deciding to torture 70 children in order to improve the health of other children. Those 70 dogs matter! Each one matters! None of them wants to die a horrible death, be killed prematurely, or spend their entire life in a kennel.

We all want our own dogs to be healthy, but people with true compassion don't want that to be at the expense of any other dogs. I'm sorry to have to say it, but in this experiment, the ends, as laudable as they are, do not justify the means.
A better way to spend the $1.25 million being raised for these experiments would be to develop an acceptable serological method to test for rabies antibodies and immunity to the rabies virus.

[Kris L. Christine]

Ms. Dozier and other PETA members have been targeting The Rabies Challenge Fund for about a week. Attacking The Rabies Challenge Fund, which seeks to save thousands of dogs' lives by funding the research with the goal of extending state-mandated rabies vaccine boosters to 5 and then 7 years will not change USDA vaccine licensing standards (which all 13 licensed rabies vaccines for dogs have gone through -- Fort Dodge, Merial, Schering-Plough, Intervet).

If PETA were truly concerned about dogs' lives, they would channel their concerns constructively and launch a massive petition to the USDA to get them to change their vaccine-licensing standards. Every member of The Rabies Challenge Fund team would applaud such a movement.

Dog owners who would like to see PETA petition the USDA to change their Code of Federal Requirements , Title 9, part 113.209 , please contact PETA's policy advisor, Samantha Dozier at samanthapeta@hotmail.com 757-622-7382 and let her know how you feel.

Below is a copy of Dr. Dodds' response to two other PETA members who have contacted her with concerns.

Unfortunately, this information from PETA is terribly misleading. See below. We've tried to have a dialog with PETA about their RCF concerns and so hope that they now understand what we're doing and why. We appreciate your concern about the way in which we must conduct the RCF Research Study. Please allow me to explain the regulatory requirements we must follow as specified by the Code of Federal Requirements, USDA , Title 9, part 113.209. We cannot get a new rabies vaccine licensed by the government with the extended booster periods of 5 and eventually 7 years unless we strictly follow these regulatory requirements. The protocol is not up to us .

The Rabies Challenge Fund is designed to prove to UDSA authorities that dogs only need two booster rabies vaccines in their lifetime. This would significantly reduce the tragedies outlined below, save countless animal pain and suffering, and still protect the public health.

The public has little understanding of how all vaccines must be tested through USDA -specified trials before they are licensed for veterinary use. Every currently licensed rabies vaccine has been required to successfully complete these specified trials; and these vaccines as you know are required by law.

Only purebred beagles raised in a dog breeding facility run by veterinarians are involved in our project. This a large USDA licensed facility maintained in strict compliance with animal care and use requirements. The dogs live in large pens and are housed together in small groups for socialization and exercise. Further socialization is provided by their caretakers.

Today, we have a formidable uphill battle compounded by inertia in trying to change outdated rabies regulations to reflect what is truly needed to protect animals and people from contracting rabies. The federal government is just not interested in promoting a uniform requirement throughout the country that rabies booster vaccinations be given every three years. A few individual states and locales still insist on mandating annual rabies boosters when these vaccines are licensed for three years by the USDA. The recent media furor over the annual rabies booster mandate by the city of Wichita, KS is but one example.

While this travesty continues under the rubrick of state's rights, countless companion animals suffer from being required to receive rabies boosters even when they're terminally ill, debilitated, very old or have a record of prior serious adverse reaction to vaccination. This usually occurs when veterinarians either don't believe that adverse events occur or are likely, or they use the excuse that they're merely following the law. This situation is further complicated when local or state authorities will not accept waivers of booster requirement even with a veterinary letter of justification and/or a rabies antibody titer beyond the 1:5 titer level deemed by CDC to be adequate for people. Just today, a distraught caregiver was faced with having to revaccinate a middle aged dog with prior history of collapse after rabies vaccine. The dog's rabies antibody titer was 1: 3125, six hundred times that required for people, and yet the local authorities refused to grant a waiver.

These all too common occurrences have resulted in an increasing number of people simply breaking the law and not vaccinating their dogs at all. However, IF these dogs injure someone, even accidentally, and they're quarantined without evidence of an in-date rabies vaccination, the public health authorities have the right to require surety and direct that the animal be killed; his/her head is then examined for rabies. One such tragedy where a family was not given the chance to appeal on behalf of their dog is in litigation as we speak.

Then, there are the heartbreaking adverse reactions and deaths that occur when animals are forced to be given rabies boosters in lieu of waivers, when justified, and the dog seizures uncontrollably and dies in the caregiver's arms. Such a case also happened this past week.

Best wishes. With reverence for all life. Jean

More information on this subject from Dr. Dodds below responding to another PETA Member's inquiry. None of the research dogs will be allowed to develop full-blown rabies (see below) and the vaccinates will survive.

1. Question: How many dogs actually suffer, per year, to make purposely killing 70 pure bread beagles acceptable?

Dr. Dodds' Reply: It has been estimated that the adverse reaction rate of aerious nature to rabies vaccinations is in the order of 0.38- 0. 50 % , with another 1-3% of vacinates experiencing less severe reactions. of the millions of dogs thatr must be vacinated by law annually.

2. Question: How long does the dog suffer with obvious rabies before he is humanely euthanized?

Dr. Dodds' Reply: Not at all ; as soon as any relevant sign is noted with round-the-clock coiverage --- at the end of the 5 and 7 year trials -- when all the dogs must be challenged with rabies virus, they are humanely sacrificed. We expect that all the non-vaccinated dogs will become ill, and that vaccinates will survive. BUT, as all these dogs will be just housed in large family style group pens, cared for and socialized for the entire trial period, without any exposure challenge to rabies virus until the end of the study, we have at least 4 years of their routine husbandry and care in which to dialog with the respoonsible USDA authorities to ask them to consider an alternative endpoint to the trial -- for example, allowing us to run rabies vaccine serolgy titers as proff of adequartete protection from rabies rather than an actual live rabies virus challenge. Dr. Schultz and I are both personally committed to work towards changing the current requirements before the end of the trials.

3. Question: What makes you believe that if an owner does not vaccinate their dog every three years because of the reaction the dog may have to the vaccination, that that same owner WILL get the dog vaccinated every five years?

Dr. Dodds' Reply: We don't, but, if the law is changed , then a dog will only need one more booster in midlife and none in old age - a biger isue if they're frail or ill. Also, remember that some states and locales within states still madate annual rabies boosters ! In Wichita, KS and Cheyenne, WY a huge recent blitz of officials challenging their ignorant position of annual rabies vaccination resulted in the city ordinances being changed for the future. Much of this effort was spearheaded by Kris Christine and the RCF. .

Question: As we all know, there’s a fine line between scientific experiments that are worthwhile for the benefits of those in the future and there are those experiments that are more harmful than what will benefit anyone in the long run! I am a firm believer that the end must justify the means and I, at this point, am not convinced that the ends of this experiment justifies the means, mainly due to the fact that I’m unsure as to how many animals, per year, truly suffer from five vaccinations in their lifetimes, rather than just three !

Dr. Dodds' Answer: Rabies vaccine is the strongest of all vaccines available today, and so elicits the highest likelihood of adverse events , including death. I deal with these tragedies almost every day from all over North America -- as does Dr. Schultz.

Actually, this is what does and will happen -- once a rabies vaccine is licensed for 5 years, a puppy would receive 2 initial doses, and then one more dose 5 years after the second one. IF we can show that a rabies vaccine can be effective and licensed for 7 years, then the dog will require one more vaccine 7 years after the second one. As it now stands, dogs are required to get a rabies booster either annually or every three years after the second one -- depending on the applicable state or local laws, and so when these privately cared for dogs become older and ill or frail - even with life-threatening diseases, most states and locales refuse to grant exemptions from rabies boosters even with justification provided by the primary care veterinarian and/or a high level of rabies antibody titer.

Poor Beagles are used in many horendous experiments.
The Huntington Lab in England does the most cruel experiments.I saw a undercover documentary on it and it was heartbreaking.
Just as us Humans have immunity once we recieve Baby vaccines and don't get them over and over and over again.
Dogs too,have such immunity and don't need annual vaccines,they are set for life.
Why is it necesary to use Beagles.
If this experimant has to be done and it is known that the results will be accepted,will they? and why can't dogs that are going to be euthenized,be used(Poor Dogs)
Is it possible these dogs will survive?
If so they should surely escape euthenasia for going through this rotten experiment.
I am just wondering how this person saw your anti experiement post on here.
The whole thing just makes me cringe.
Also if these dogs do contract Rabies,will they be quickly put out of their misery.
Lots of ethical questions.
Once again,poor animals,such a test would never be done on Humans.

It's interesting that the Rabies Challenge Fund folks are now saying they will attempt to make changes to the protocol after the experiments have begun on beagles (even though it is highly unlikely the USDA will agree to that since the experiments have already begun). So it is still likely that many dogs will die and many will die excruciating deaths.

As far as I can tell, RCF has made no attempts to date to get a serological protocol approved. The experiments being conducted by RCF are purely elective. Why not design a tenable serological protocol that can be approved by USDA? A serological method would allow data to be collected from volunteers rather than dogs stuck in a laboratory. Why were none of these efforts made before PETA began to shine a spotlight on the myriad of problems with RCF's plans?

With regards to RCF's statement that PETA should be working on this issue, we are indeed working on non-animal protocols for vaccine testing at both the USDA and the FDA. PETA has spent more than a quarter million dollars in recent years to develop non-animal testing methods. We're very happy to put our money where our mouth is!

Despite repeated requests, the RCF folks have refused to provide details including:

. the actual number of dogs involved in each study. The USDA gives only the minimum number of dogs that they must have data for at the culmination of the study, so logically RCF must use more dogs than the USDA's minimum of 70. However, RCF will not even answer this simple question.

. the conditions and socialization for the dogs. Dodds referred PETA to USDA's protocol for this information. USDA's protocol does not specify that dogs should be socialized or that they should receive toys or even a bed.

. how and when the dogs would be killed. RCF referred PETA to the USDA protocol for this information. USDA's protocol stipulates that even vaccinated dogs are to be killed and their brains examined. This is in direct contradiction RCF's current claim that it will adopt out the dogs who don't die.

RCF makes it appear that dogs will be killed at the first signs of rabies. Rabies is painful and its symptoms can begin quietly. Dogs will likely die of painful complications related to paralysis and inability to breathe.

No one is disputing how the immune system works and that dogs are most likely being over-vaccinated in many ways. However, a way to combat this is not to launch yet another study that will kill even more dogs.

Much more good could have come from an effort to change the way rabies vaccine efficacy is tested rather than to use more than $1 million to kill beagles.

We encourage the RCF to do better! They could not be doing much worse.

I saw a TV doucmentary once,where they blow torched a Pig,it was said it was to enhanch burn treatment.I am the medical field and the types of burns and how they heal,is is long been known.
The test of Rabbits where they suture their eyes shut and put in caustic materials has finally ended after thousand of innocent rabbits,sufferd terrible pain.
I have read of other such tets where the resuts were already known.
It seems drug compaines.some organizations etc. must prove they are worth something.A money raiser!
It seems the Rabies testing results haven't got any type of known approval and these poor dogs are going to have to indure a miserabe painful death.
I have to think any dog living under such stressful conditons,would have a strike against their immunity.
I just think these people are out to get themselves some highly publicised attention but it is negative to be sure.
Find another way please for the sake of the Dogs you are putting a death warrant on.

[Kris L. Christine]

PETA member, Samantha Dozier, failed to disclose the following in her post.

April 28, 2008 Newsweek article entitled PETA and Euthanasia by Jeneen Interlandi PETA and Euthanasia | Newsweek Newsweek: Management | Newsweek.com

"Since 1998 PETA has killed more than 17,000 animals, nearly 85 percent of all those it has rescued."

[Kris L. Christine]

From Channel 3 News in Kentucky May 7, 2008: PETA killed 'companion animals' | KY3 | Trends

OVER 90 PERCENT PUT TO DEATH

"WASHINGTON -- An official report filed by People for The Ethical Treatment of Animals (PETA) with the Virginia government shows that the organization put to death more than 90 percent of the dogs, cats, and other pets it took in for adoption during 2007. "

Plese don't deflect from the question and the points made here.
This is my opinion,I am not a PETA person,in fact while they have educated people to animal crulety,including the farming industry,which has made me a vegetarian,I don't agree with their crazy beliefs.They have turned show dogs out onto highways,they don't believe animals should be pets,seeing eye dogs ect. and have euthenized them.In fact they wold rather see all animals be stamped out than held by Humans.They are off base,if you ask me and much,if not most has to do with the money they get.Only a fraction of it is spent on animals and I have never read about an animal shelter.A quarter million dollars they are bragging about spending in a post I read,it nothing compared to the money they haul in.
I dislike PETA with a passion.They are a cult in my opinion.
Please stick to the subject.Just like a Politicain,they always try to steer away from the point,when they are afraid of the truth.
I am writing about this Rabies Challenge and you know it.You certainly are protesting too much,a sure sign of a guilty conscience!!!!!!

[Kris L. Christine]

Guilty Conscience? For what precisely?

The Rabies Challenge Fund has never tried to hide the fact that we are financing challenge studies -- if you look at our title, website, press releases, the word challenge is everywhere.

We are funding research that could save the lives of thousands of dogs, it is not our protocol, but rather the USDA's, that requires euthanization of the study animals -- it would be wonderful if PETA would initiate an effort to change them.

My point in posting the 2 PETA stories above is to show PETA'S incredible hypocrisy for euthanizing thousands of animals they took in for adoption (for what purpose?) and then pointing the finger at The Rabies Challenge Fund for financing research in which the USDA mandates euthanization of 40 animals. Because USDA regulations require it, in 5 years (if PETA does not take action to change Title 9, part 113.209), 40 dogs in the rabies challenge studies will be euthanized according to those regulations -- the purpose of conducting those studies is to save the lives and well-being of thousands of dogs.

Every member of The Rabies Challenge Fund regrets that the USDA requires euthanization of the challenge study animals.

Perhaps if you are concerned enough, you will take action at your own cost to change Title 9, Part 113.209, as The Rabies Challenge Fund team has taken action action at our own cost with the hope of extending state-mandated rabies laws from 5 to 7 years.

[Kris L. Christine]

Channel 5 News WCVB Boston Woman: Rabies Shot Killed my Poodle May 28, 2008

Woman: Rabies Shot Killed My Poodle - Boston News Story - WCVB Boston

[Kris L. Christine]

PETA launched a public attack on The Rabies Challenge Fund in April this year, the allegations of which have appeared on various dog discussion boards and chat lists. For those of you who may have seen those posts, below is an updated copy of Dr. Dodds' response to PETA'S allegations-- her responses are in red. Beneath that is information I compiled which may help dog owners understand why this research is necessary.

Please see the series of e-mails and my responses to PETA. You'll see that I did answer each letter in good faith in a timely manner and not as alleged by Dr. Dozier. Additional information and responses are below.

By the way, perhaps the current PETA people are unaware that over the years I've provided PETA --- upon their request -- pro-bono extensive review and scientific opinion about the research records obtained under FOIA concerning certain inhumane, invasive primate research experiments. I've been roundly criticized by my peers for this activity, as you can well imagine ! I'm the Past -President of the Scientist's Center for Animal Welfare and a 20 + year member of AVAR -- the Association of Veterinarians for Animal Rights -- which has now joined HSUS; among other long standing activities in the humane community (40 + years).

Here at last are my responses to the further comments on the RCF protocol and PETA's allegations. Under separate cover, I'm forwarding you the actual letters I sent the 2 people at PETA upon their initial and repeat inquiries. You'll see that I answered them immediately and forthrightly.

Jean (W. Jean Dodds, DVM)

Thank you for your email regarding the Rabies Challenge Fund (RCF). Please be aware that we attempted to correspond with W. Jean Dodds (co-trustee and veterinarian responsible for the RCF) for a number of weeks in April and May of this year. During that time, we tried to clarify a number of issues surrounding the RCF experiments, yet we received nothing of substance in response to our questions.

We have repeatedly asked the study organizers:

1. To supply a copy of the protocol so that we (and other experts who collaborate with PETA) might help redesign the study so that dogs are not killed at the end of the study, and so that the study might be done in the most humane way possible). Did that in an attachment to my first response to PETA.

2. The number of dogs to be used as part of the two concurrent studies, how far along the study had progressed (have the dogs been purchased from a laboratory animal supplier, have they been vaccinated, are they already housed in the RCF facilities, etc.). Answered that too. The study began last fall, as described.

3. What efforts RCF had made to avoid killing all of the dogs they are using in their study. Dr. Ron Schultz has undertaken informal dialog with USDA senior officials , in his capacity as advisor to the vaccine industry and regulatory body. He has decades of experience in the field and attends meetings with these folks regularly. At this point, we have not made progress in changing their views, BUT, he and I together are planning to present a more formal proposal to them. We have 4 + years to accomplish what we view as an important need to change the regulations as currently written for endpoint challenge testing -- before anything involving challenge of these healthy dogs (vaccinates and controls) with rabies virus has to take place according to the current regulatory protocol.

In Dodd’s last response, (the third letter without substantive information), she told us she did not have the information we were seeking and referred our questions to another scientist responsible for the study – Ronald Schultz. Please read my direct correspondence here. We never received any response from Schultz. Dr. Schultz is a very busy Department Chairman, teacher, and world respected vaccinology scientist. I do not know if he directly answered any remaining questions PETA raised -- certainly we have nothing to hide here.

It is interesting that the Rabies Challenge Fund folks are now saying they will attempt to make changes to the protocol after the experiments have begun on the dogs (even though it is highly unlikely the USDA will agree to that since the experiments have already begun). Nonsense. This has nothing whatsoever to do with the fact that the study has begun, because no procedures related to challenge with rabies virus will take place for 4 + years. We have the interim years to dialog with the federal authorities, based upon Dr. Schultz's expertise, and hope to amend the CFR regulatory requirements for the end phase of their protocol. So it is still likely that many dogs will die and many will die excruciating deaths. Absolutely untrue; all the vaccinates should be healthy and survive challenge. Even if we're forced by the USDA to follow the current challenge protocol at the end of the 5 and 7 year studies, there will be no excruciating deaths among the control dogs, because at the very first evidence of malaise and illness they will be sacrificed. The existing data on rabies challenge trials that were completed for each currently licensed rabies vaccine tells us what to expect as far as the number of days before any sign of illness in the challenged control dogs shows up. Remember, this is a fatal mammalian disease, so animal caretakers in these facilities will be ever vigilant to spot the first signs of malaise and illness.

continued below

[Kris L. Christine]

continued from above

As far as we can tell, RCF has made no attempts to date to get a serological protocol approved [i.e, titer testing commonly offered at many vet offices to accurately detect the concentration of rabies antibodies at any interval post-vaccination]. That is not true; most rabies titers done in the county today are to satisfy export requirements for animals moving to rabies-free countries. Relatively few clinical vets check rabies titers for purposes of getting exemption waivers as justified only on a case-by-case basis, and requiring approval by local public health regulatory authorities. In fact most vets don't even realize that such tests can be done. The experiments being conducted by RCF are purely elective. Also not true. Why not design a tenable serological protocol that can be approved by USDA? They have always deigned such methodology and every year the US State and Territorial Public Health Officials unequivocally state that rabies titer serology is unacceptable and unreliable -- this year's reiteration was published in a May 2008 issue of the JAVMA. A serological method would allow data to be collected from volunteers rather than dogs stuck in a laboratory. No , it will not suffice . I don't know whether the PETA people are completely naive here, or knowingly suggesting something to mislead their supporters into thinking that we've not thought of or tried to get such testing allowed. Why were none of these efforts made before PETA began to shine a spotlight on the myriad of problems with RCF’s plans? This presumption without evidence to support their contention is perhaps arrogant. These alternative suggestions have been made for years by myself, Dr. Schultz and others; they have been the subject of seminars, publications, and teaching handouts to both the profession and the public.

With regards to RCF's statement that PETA should be working on this issue, we are indeed working on non-animal protocols for vaccine testing at both the USDA and the FDA. PETA has spent more than three quarters of a million dollars in recent years to develop non-animal testing methods. We're very happy to put our money where our mouth is! IF that's true; we applaud the effort !

Despite repeated requests, the RCF folks have refused to provide details including:

• the actual number of dogs involved in each study. The USDA gives only the minimum number of dogs that they must have data for at the culmination of the study, so logically RCF must use more dogs than the USDA’s minimum of 70. No we only need a few extra animals (should a few become ill during the length of the study for some unforeseen natural disease), and we will not use more from both humane and cost issues. However, RCF has not answered even this simple question.

• the conditions and socialization for the dogs. Dodds referred PETA to USDA’s protocol for this information. USDA’s protocol does not specify that dogs should be socialized, group housed, or that they should receive toys or even a bed. The existing USDA CFR protocol is outdated in that regard, and the law has not been updated, BUT, as we and PETA all realize, all current research protocols are governed by the USDA Animal Welfare Act and the NIH Guide for the Care and Use of Laboratory Animals for all institutions that receive federal research monies. These regulations require socialization and exercise and specify the animal housing conditions. So, this point is moot and they're certainly are well aware of the current federal and state rules that apply.

• how and when the dogs would be killed. RCF referred PETA to the USDA protocol for this information. USDA’s protocol stipulates that even vaccinated dogs are to be killed and their brains examined. At the end of the 5 and 7 year studies, the current regulations do so state, but see above for our plans to get some amendments accepted in the interim years. This is in direct contradiction RCF’s current claim that it will adopt out the dogs who don't die.No one in an official capacity for the RCF or any one else purporting to represent us, to my knowledge, has ever said that. It would create a huge liability issue.

RCF makes it appear that dogs will be killed at the first signs of rabies. Rabies is painful and its symptoms can begin quietly. See above. Dogs will likely die of painful complications related to paralysis and inability to breathe. Not true; the end point will be recognized long before this end stage of paralysis.

No one is disputing how the immune system works and that dogs are most likely being over-vaccinated in many ways. However, much more good could have come from an effort to change the way rabies vaccine efficacy is tested rather than to use more than $1 million to kill beagles. This is just inflammatory rhetoric.

To paraphrase PETA's president, "A dog is a dog is a dog is a dog." It is unfortunate the RCF chose to use crude and cruel methods in its attempts to help other dogs." It is also unfortunate that PETA chooses to paint our good will for the benefit of millions in this light.

It seems there are critical differences here, and I stand with PETA and again demand (hey -- how about a request rather than demand here ?) the issues raised by PETA be addressed AND FOLLOWED.

Below is a copy of Dr. Dodds' previous responses to two other PETA members who have contacted her with concerns.

Unfortunately, this information from PETA is terribly misleading. See below. We've tried to have a dialog with PETA about their RCF concerns and so hope that they now understand what we're doing and why. We appreciate your concern about the way in which we must conduct the RCF Research Study. Please allow me to explain the regulatory requirements we must follow as specified by the Code of Federal Requirements, USDA , Title 9, part 113.209. We cannot get a new rabies vaccine licensed by the government with the extended booster periods of 5 and eventually 7 years unless we strictly follow these regulatory requirements. The protocol is not up to us .

The Rabies Challenge Fund is designed to prove to UDSA authorities that dogs only need two booster rabies vaccines in their lifetime. This would significantly reduce the tragedies outlined below, save countless animal pain and suffering, and still protect the public health.

The public has little understanding of how all vaccines must be tested through USDA -specified trials before they are licensed for veterinary use. Every currently licensed rabies vaccine has been required to successfully complete these specified trials; and these vaccines as you know are required by law.

Only purebred beagles raised in a dog breeding facility run by veterinarians are involved in our project. This a large USDA licensed facility maintained in strict compliance with animal care and use requirements. The dogs live in large pens and are housed together in small groups for socialization and exercise. Further socialization is provided by their caretakers.

Today, we have a formidable uphill battle compounded by inertia in trying to change outdated rabies regulations to reflect what is truly needed to protect animals and people from contracting rabies. The federal government is just not interested in promoting a uniform requirement throughout the country that rabies booster vaccinations be given every three years. A few individual states and locales still insist on mandating annual rabies boosters when these vaccines are licensed for three years by the USDA. The recent media furor over the annual rabies booster mandate by the city of Wichita, KS is but one example.

While this travesty continues under the rubric of state's rights, countless companion animals suffer from being required to receive rabies boosters even when they're terminally ill, debilitated, very old or have a record of prior serious adverse reaction to vaccination. This usually occurs when veterinarians either don't believe that adverse events occur or are likely, or they use the excuse that they're merely following the law. This situation is further complicated when local or state authorities will not accept waivers of booster requirement even with a veterinary letter of justification and/or a rabies antibody titer beyond the 1:5 titer level deemed by CDC to be adequate for people. Just today, a distraught caregiver was faced with having to revaccinate a middle aged dog with prior history of collapse after rabies vaccine. The dog's rabies antibody titer was 1: 3125, six hundred times that required for people, and yet the local authorities refused to grant a waiver.

These all too common occurrences have resulted in an increasing number of people simply breaking the law and not vaccinating their dogs at all. However, IF these dogs injure someone, even accidentally, and they're quarantined without evidence of an in-date rabies vaccination, the public health authorities have the right to require surety and direct that the animal be killed; his/her head is then examined for rabies. One such tragedy where a family was not given the chance to appeal on behalf of their dog is in litigation as we speak.

Then, there are the heartbreaking adverse reactions and deaths that occur when animals are forced to be given rabies boosters in lieu of waivers, when justified, and the dog seizures uncontrollably and dies in the caregiver's arms. Such a case also happened this past week.

Best wishes. With reverence for all life. Jean

continued below

[Kris L. Christine]

continued from above

More information on this subject from Dr. Dodds below responding to another PETA Member's inquiry. None of the research dogs will be allowed to develop full-blown rabies (see below).

1. Question: How many dogs actually suffer, per year, to make purposely killing 70 pure bread beagles acceptable?

Dr. Dodds' Reply: It has been estimated that the adverse reaction rate of a serious nature to rabies vaccinations is in the order of 0.38- 0. 50 % , with another 1-3% of vaccinates experiencing less severe reactions. of the millions of dogs that must be vaccinated by law annually.

2. Question: How long does the dog suffer with obvious rabies before he is humanely euthanized?

Dr. Dodds' Reply: Not at all ; as soon as any relevant sign is noted with round-the-clock coverage --- at the end of the 5 and 7 year trials -- when all the dogs must be challenged with rabies virus, they are humanely sacrificed. We expect that all the non-vaccinated dogs will become ill, and that vaccinates will survive. BUT, as all these dogs will be just housed in large family style group pens, cared for and socialized for the entire trial period, without any exposure challenge to rabies virus until the end of the study, we have at least 4 years of their routine husbandry and care in which to dialog with the responsible USDA authorities to ask them to consider an alternative endpoint to the trial -- for example, allowing us to run rabies vaccine serology titers as proof of adequate protection from rabies rather than an actual live rabies virus challenge. Dr. Schultz and I are both personally committed to work towards changing the current requirements before the end of the trials.

3. Question: What makes you believe that if an owner does not vaccinate their dog every three years because of the reaction the dog may have to the vaccination, that that same owner WILL get the dog vaccinated every five years?

Dr. Dodds' Reply: We don't, but, if the law is changed , then a dog will only need one more booster in midlife and none in old age - a bigger issue if they're frail or ill. Also, remember that some states and locales within states still mandate annual rabies boosters ! In Wichita, KS and Cheyenne, WY a huge recent blitz of officials challenging their ignorant position of annual rabies vaccination resulted in the city ordinances being changed for the future. Much of this effort was spearheaded by Kris Christine and the RCF.

Question: As we all know, there’s a fine line between scientific experiments that are worthwhile for the benefits of those in the future and there are those experiments that are more harmful than what will benefit anyone in the long run! I am a firm believer that the end must justify the means and I, at this point, am not convinced that the ends of this experiment justifies the means, mainly due to the fact that I’m unsure as to how many animals, per year, truly suffer from five vaccinations in their lifetimes, rather than just three !

Dr. Dodds' Answer: Rabies vaccine is the strongest of all vaccines available today, and so elicits the highest likelihood of adverse events , including death. I deal with these tragedies almost every day from all over North America -- as does Dr. Schultz.

Actually, this is what does and will happen -- once a rabies vaccine is licensed for 5 years, a puppy would receive 2 initial doses, and then one more dose 5 years after the second one. IF we can show that a rabies vaccine can be effective and licensed for 7 years, then the dog will require one more vaccine 7 years after the second one. As it now stands, dogs are required to get a rabies booster either annually or every three years after the second one -- depending on the applicable state or local laws, and so when these privately cared for dogs become older and ill or frail - even with life-threatening diseases, most states and locales refuse to grant exemptions from rabies boosters even with justification provided by the primary care veterinarian and/or a high level of rabies antibody titer.
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The following information was compiled by Kris L. Christine:

Were the states to extend their rabies booster requirements without USDA Title 9, part 113.209 challenge studies, accept rabies titers in lieu of vaccination, or recognize the 1992 French rabies challenge study results demonstrating a minimum 5 year duration of immunity, this research would not be necessary. The Rabies Challenge Fund seeks to save the lives of thousands of dogs and millions of others from suffering vaccinal adverse reactions.

If the USDA does not change their vaccine licensing requirements upon which all state rabies immunizations laws are currently based, Title 9 Part 113.209, by the time the first challenge is conducted in 4 1/2 years, then 35 of the dogs will be required to be euthanized and their brain tissue tested for rabies according to USDA's standard. Dr. Dodds and Dr. Schultz are committed to trying to get the USDA to change that requirement, and we're all very much hoping that they will be successful.

Looking specifically at the number of dogs for whom "death" is an adverse reaction to rabies shots within days (not taking into account those which develop cancers and other disorders over the course of several weeks or months) of vaccination, 1,250 dogs a year could be saved if the challenge studies are successful and states adopt the extended booster protocols.

The Journal of the American Veterinary Medical Association has published a report in its April 1, 2008 issue, Vol. 232, No. 7, entitled: Postmarketing Surveillance of Rabies Vaccines for Dogs to Evaluate Safety and Efficacy."

Despite the extreme under-reporting of vaccinal adverse reactions, this report states on the second page that between April 1, 2004 and March 31, 2007, the Center for Veterinary Biologics, "nearly 10,000 adverse event reports (all animal species) were received by manufacturers of rabies vaccines..........Approximately 65% of the manufacturer's reports involved dogs."

The report further states on the second page that: "Rabies vaccines are the most common group of biological products identified in adverse event reports received by the CVB," and they give the following description of the adverse reaction followed by the % of dogs affected: Vomiting-28.1%, Facial Swelling-26.3%, Injection Site Swelling or Lump-19.4%, Lethargy-12%, Urticaria-10.1%, Circulatory shock-8.3%, Injection site pain-7.4%, Pruritus-7.4%, Injection site alopecia or hair loss-6.9%, Death-5.5%, Lack of Consciousness-5.5, Diarrhea-4.6%, Hypersensitivity (not specified)-4.6%, Fever-4.1%, Anaphylaxis-2.8%, Ataxia-2.8%, Lameness-2.8%, General signs of pain-2.3%, Hyperactivity-2.3%, Injection site scab or crust-2.3%, Muscle tremor-2.3%, Tachycardia-2.3%, and Thrombocytopenia-2.3%.

Veterinarians are not required by law to report adverse reactions to vaccines, to which the World Small Animal Veterinary Association stated in their 2007 Vaccine Guidelines that there is: "gross under-reporting of vaccine-associated adverse events which impedes knowledge of the ongoing safety of these products," and in an article entitled, A New Approach to Reporting Medication and Device Adverse Effects and Product Problems, (JAMA - June 2, 1993. Vol.269, No.21. p.2785) Dr. David Kessler, former head of the Food & Drug Administration, reported that "only about 1% of serious events are reported to the FDA."

In light of the 10,000 adverse reactions to the rabies vaccine in the JAVMA report, 65% of which were in dogs, the estimated 1% reporting of "serious" events by the former head of the FDA means that the actual number of dogs that had adverse reactions to the vaccine would be more like 650,000 -- applying the 5.5% figure given by the CVB resulting in death indicates that 3,750 died over the same 3 year period (1,250 a year or 6,250 over the course of 5 years, or 8,750 over the course of 7 years).

Since April, PETA has been targeting The Rabies Challenge Fund, which seeks to save the lives of thousands of dogs and ensure the well-being of millions of others by funding research with the goal of extending state-mandated rabies vaccination boosters from 3 to 5, and then hopefully 7 years.. If PETA is truly concerned about dogs' lives, they will channel their concerns constructively and launch a massive petition to the USDA to get them to change their vaccine-licensing standards. Every member of The Rabies Challenge Fund team would applaud such a movement.

Dog owners who would like to see PETA petition the USDA to change their Code of Federal Requirements , Title 9, part 113.209 , please contact PETA's policy advisor, Samantha Dozier at samanthapeta@hotmail.com 757-622-7382 and let her know how you feel.

Most house dogs has rabies vaccine injection except wild animal that you must becareful not to be bitten by them.

dog rabies symptoms

Do you think that Obama is going to win because the Republicans have such a bad candidate?
Why did John McCain make his final argument against Obama... coal?
That's his closing argument? William Ayers, Rev. Wright, spreading the wealth, Born Alive, meeting dictators without preconditions, etc. all have to take a back seat so that McCain can go to Colorado and New Mexico to talk about coal? Does this more or less explain why he's going to get his clock cleaned Tuesday?