Hi there!
I personally have a mutt, but my bestfriend is a yorkie freak, and she's had quite a few, and her mother breeds them and boards them ( doggie daycare type of thing)
So far the biggest thing I have seen with her yokies and yorky puppies is the grooming! If you are brave enough to do it yourself, you'll save alot, but the groomers are the most expensive thing I have noticed. They are such a small dog breed, I would be scared to do it myself personally but My friends mother and my friend do their own grooming.
So far vet bills with them included neutering, tooth removal, annual shots and heat stroke.
Hope this helps!
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