[CorkyMax]

Sorry, but I am going to be blunt I guess! She may or may not have diabetes. I would at this point not focus as much on that as I would be more inclined to think all the things that are going on with her right now is a result of the Proin itself causing all these symptoms--The thing to worry about right now--Has this med (or is it in the process) destroyed her liver or kidneys---Is her life still in danger! If you give the vet the idea of Diabetes--that will prob. be all he focuses on and what about possible liver or kidney failure because of the proin---Vets do not want to believe proin is dangerous to start with!! Acting strange is one of the things I would associate with the damage this crap has already done --as well as everything else that is happening. I am going to email a friend who has posted in here about what happened to her dog (Jasmine)--Cheryl Martin--She can tell you much more than I can. Her dog went through hell for many days before dying. Please keep checking back here for a reply from her--May take a little while

Sorry to be so blunt but I think you should get that blood work done as soon as possible and hopefully if things are really bad--something can be started to try and get your dog healthy!

[Duke's Mom]

About two weeks ago our 13 year old German Shepherd, Duke, started having incontinence problems. We took him to our vet on Monday, January 17th. Our vet performed a through exam along with a complete blood panel and complete urinalysis. The blood results were all ok so we decided to try proin for the incontinence issue. He was prescribed 1 pill three times a day. We started giving Duke the pills on Wednesday morning. He has always been very good about taking pills, but I had to fight with him to take these. On Friday afternoon I noticed he had vomited in our yard 2 times. We stopped giving Duke the medication but it was too late. Friday night he started having trouble walking. I thought maybe he was stiff because he had tender hips (being 13) and it was very cold out. For a second, I thought maybe it was the medicine but he seemed fine other wise and was acting normal. Saturday morning Duke was still walking funny and within an hour he was falling into things and started acting anxious and incoherient. I took him back to the vet and another blood panel was done. I was told to come back in an hour to get the blood results. When we returned his blood results were again fine but the vet explained that he may have had a stroke and it may have been from the proin. I was devistated! I wish I had researched the medication before I gave it to him. We discussed the options and as my mind was reeling from the information... Duke had a severe stroke. I immediately made the decision to euthanise. I have NEVER experienced anything like that in my whole life! Everything happened so fast! Wednesday he started taking the pills and by Saturday he was gone! I wanted to share Duke's story because if I had done my research on the medication I would NOT have given it to him. I do not in any way blame the vet because you have no way of knowing what type of reactions each animal will have. She never had this happen before either. Duke's death was very tragic for us, and I am just hoping that Duke's story will help others. My heart goes out to all pet owners who have lost a loved one!

[DimitarMKD]

Hello
I have a french puddle 12.5 years old. She has been sprayed 3 years ago she has been great ever since until last summer when i noticed an opening close to her vaginal opening. I took her to my vet and i was told it was kind of a tumor and she needs to undergo cytostatics. She took 3 shots every 3 days and after that she started wetting. I thought that it might be a result from the chemo (I didn't have any other clue until i read this forum). She then stopped wetting for 2-3 months and then again started (i blamed it on the cold weather and her age as her vet is constantly saying which pisses me off). She started peeing again all the time even right after she's been taken out. She took another shot of cytostatics 2 weeks ago as we were told she had to take one more for safety 6 months after the first shots (although she had no signs of anything else part wetting). And as main explaination for her wetting was her AGE!This sounded rediculous to me and since my mom is a nurse with 38 years of working experience, she got on to the symptoms of urinary bladder weak muscles and she even said that our dog might have diabetes!!!! I live in a f&*(& up country where humans dont get medical care not animals. So i realized of calling the vet who made the surgery to my dog (he lives in the capital, Skopje) to ask if he can provide with blood tests to check up on her diabetes first. I won't be agreeing on Proin by any chance!!! Thanks for your discussions it really helped me!

[Dobiemom]

I’m so sorry to hear about folks losing their beloved pups. I can’t imagine losing my ‘kids’ to something that’s possibly preventable. However, I have to say that Proin is not the “evil empire” that much of this thread is making it out to be…

My doberman, Jessie, has had urinary incontinence issues since she was a puppy. Our vet started her on Proin at about 7 months old. She’s now nearly 9 years old, and has been taking Proin essentially all of her life. Jessie is 98 lbs now, takes 50mg Proin tablets three times per day (150mg per day), and is the picture of health. She’s never experienced any side effects from it, and she is one of the happiest, mellow, friendly and even-tempered dobes we’ve ever had (just ask her little brother, Tucker!).

The only thing that Proin has done for Jessie over the years is to prevent “Lake Jessie”. She sleeps on our bed, and you can imagine the result of missing a couple of tablets… upsetting for her, and a mess for us. Proin has greatly improved Jessie’s quality of life. We now believe that spaying her at a young age may have contributed to her incontinence, so we will likely re-think that with any other female dogs we may have someday.

Having read this thread, I believe that I will be more cautious with future dogs if Proin is prescribed for them. It sounds like although Proin is a lifesaver for many/most, it could be a death sentence for others. The problem is that there apparently is no rhyme or reason as to which dogs will be affected either way. Some more testing must be done!

[nncydrw]

Nancy Drew is a female lab around 6-8 years, weighs 65lbs and is active and healthy. 2 days ago started dripping urine. Vet prescribed Proin 1 to 2 tablets per day. Before discovering this thread, gave her only 1 pill and watched her reaction very closely. Became very lethargic, lying in the corner growning in discomfort. Then at one point got up and started walking around with a disoriented look and was panting very heavily; house was not hot, it was the meds. Did not have her usual spark and growned through the night in some degree of discomfort.

Definitely had an adverse reaction to Proin. Good news, she seems to be pretty much back to normal this morning. SOO glad I found this thread before it could have been too late! I will no longer be giving Proin to her and plan to try soy milk treatment if urine dripping continues.

Will report a problem/adverse reaction to Proin to FDA. I URGE others to explore natural treatments given my experience and information in this post.

[CorkyMax]

I am so glad you caught this in time--You were lucky as some dogs have died after only one pill!!

I don't know how many of these posts you read or how much info you have on how to report this so I am putting a link here now for reporting it---It is good to repeat this link anyhow for more people to see it: http://www.dogsadversereactions.com/fdasuspect.html

[stewie]

I am so glad I found this forum and thread. My little chihuahua, Pedro, was put on proin 2 days ago. Yesterday he did not act like himself at all. He was lethargic and seemed disoriented. This morning he is better, but still not himself. He will not be getting any more of this garbage. Thanks to all of you for your information. You have saved my dog's life. I just decided to google proin to read about it and found this site. Can anyone tell me of a natural bladder control product. Pedro had surgery on his right back leg and has a bandage on it. He is only three and I think the bladder control problem is temporary. Thanks again everyone for your warnings.
To those of you who lost their beloved pet, I am so sorry.

My goal in life is to be the person my dog thinks I am.

[CorkyMax]

I am so glad you found out about that dog killer-proin!
You asked if there was anything else that would work--I have not had this problem so have not tried anything but if you go back and read over the many posts in this thread--I know others have mentioned things. Here is one member's reply: I found a good Proin alternative
Joined the group just so I could let others know about this product. My dog Sonie was on Proin due to spay incontinence. It got so bad at one point she would leak about half of the time she lay down. She was put on Proin. She was already a very nervous dog and I felt it made her more anxious. I started this supplement as I gradually decreased her Proin dosage over the course of a month. Now she is completely on this supplement and completely off of the Proin. Still no leaks, it works great!

Since I'm new it's not letting me post a link. But the product is called Senior Bladder Support by NaturVet It is widely available online and at Petco.

I hope you will report this to your vet and --See the link I gave for reporting to the necessary places above in my last post!! (Corky/Max) Help try to save another dog's life by trying to get this killer drug off the market!

[stewie]

Thanks Corkey/Max for the reply. I am happy to meet a fellow dog lover. I am so glad everyone posted their warnings about proin. If it isn't fit for humans why give it to dogs?
I don't think I can report the vet. I believe he was doing what he thought was best. Besides it is legal so he did nothing I can report him for. Thanks again!

[CorkyMax]

Originally Posted by stewie

Thanks Corkey/Max for the reply. I am happy to meet a fellow dog lover. I am so glad everyone posted their warnings about proin. If it isn't fit for humans why give it to dogs?
I don't think I can report the vet. I believe he was doing what he thought was best. Besides it is legal so he did nothing I can report him for. Thanks again!

You misunderstood me---You don't report the vet---You report what happened to your vet so he can also log it and keep track of dogs having reactions to proin and hopefully he will get the message that proin is very dangerous for dogs----Better yet--Give him the link to this thread/posts in this forum so he can read what is happening!! He is suppose to report the incident too. How else will the idiots know what is happening if it is not reported?!!

[stewie]

Sorry I misunderstood you. I did call my vet and talked to his assistant. I told her about Pedro's reaction and what I had read on this forum. I also told her to just google the medication and she would find out a lot of people have had problems. Thanks again

[CorkyMax]

Thank you! If more people who had problems with this proin and bothered to report it----Maybe it could get banned from use. Many dogs could be saved!! I just wonder how many dogs have died because of this killer drug and even the dog owner had no idea that it was the cause!

[stewie]

Good morning, I got your reply later last night. I was out all day yesterday.
I emailed my friend who gave me Pedro and told her about what had happened and about proin She has several dogs and I wouldn't want anything to happen to them. She loves all of them so, it would break her heart. I also told her about this website. Have a great day. See you later.::

[antieuthanasia]

HI. What you think about euthanasia?:shock:

If you like dogs, you can contribute to our cause as well. Romania is getting ready to euthanize hundreds of thousands of stray dogs. Help us create shelters, find homes, give food, neuter and fight the government against this law. Every little thing counts towards saving the lives of our best friends. "Say NO To Stray Dogs Euthanasia"

[mkper]

I wish I had found this forum before we gave our 13-year-old Siberian Husky the Proin pills prescribed by our Vet for her slight incontinence. He prescribed them at her appointment for her distemper shot and physical checkup, where he pronounced her to be in excellent shape. She then took a 50-mg tablet twice a day for the following 13 days before we almost lost her. I didn't notice anything unusual until that last day when she became very 'hyper', paced in circles when she was not wandering through every room in the house (acting like she was having a 'panic attack'), and her eyes had a strange look. She couldn't relax or stop panting and her tongue hung down 5-6 inches from the side of her mouth. She also drank water constantly, or so I thought until I noticed that her fur below both sides of her mouth was dripping wet. I later realized that her tongue must have been swollen and the water she was trying to lap up was just running down her chin. I quit giving her the Proin pills right then (she did not get her second Saturday pill) and would have called the Vet except it was Saturday evening and you cannot get a Vet in this town on weekends. I got her calmed down some and by the next morning she was acting like her old self and has been ever since. I think (hope) I stopped the pills in time and she did not have a slight stroke. I am now looking into information about 'Senior Bladder Support' by NaturVet Natural Solutions. I'd be interested in hearing about anyone's experience with this.

[gizmotlt]

I gave my 14 year old lab mix Proin after my vet recommended it. He has never had any accidents in the house before but had started peeing in his sleep. When I gave him the first pill he paced continuously. He finally laid down and panted so bad that I sat there and fanned him until he finally quit. I gave him another pill later that day and he did the same thing except worse. I sat up almost all night and watched him because I was so afraid that I had given him something that was going to kill him. I looked up Proin on the internet the next morning and saw that alot of other people experienced the same thing with their pet. I will never give another pet that medication again. The vet did say he had a slight urinary tract infection and gave him Clavamox. Since he has been on it he has not had any more accidents. I even had to refill it. The first prescription did not seem to be enough. Hopefully this will take care of the problem but if not I will just keep the waterproof covers on my furniture. I am sorry for all of the losses of pets that fell victim to the drug.

[cherylmartin]

To All ProIn Victims:

As the anniversary of the loss of my beloved Jasmine approaches, each and every notice I read reopens a saddness and guilt that is indescribable.
Even though I have since adopted a marvelous Schnorkie Stella, the memories of the pain and suffering Jasmine went through after 2 doses of ProIn are as vivid as if it were July 2009 again.
I cry for all of you.
My heart also is cying out for you to report these cases to the FDA! It is so important that they know of ANY adverse reaction even if you were fortunate enough to have a surviving pet. If those of us who have witnessed an adverse reaction from the use of ProIn and we DON'T do any thing, we are guilty of allowing another furbaby to be given this deadly drug and die a horrbile death.

[Salamander]

Sorry to double-post but *this* ongoing thread probably saved my girl from the horror of Proin.

However, I have questions that need answering.

Here is the same post I made on a separate thread:

Thanks to the people here whose posts warned me from allowing Proin to be given to my girl, my vet agreed, albeit reluctantly, to prescribe Estriol for her.




He has never used it before and has no idea of the correct dosage.

The dog in question is a spayed 4 year old Portuguese Podengo Medio who weighs 30 pounds.

Can anyone help me with the correct dosage?

I also intend to contact the company once the medicine has arrived but thought I'd ask here first, since it was this forum who saved her from the risking the nasty Proin regimen.

*Any* help or advice would be greatly appreciated!

Many very grateful thanks to all who warned me away from Proin and set me on the path to discover the dangers of it.

I wasn't crazy about it anyway as one of my Ibizan hounds' sisters was put on it and became a psycho who alternately attacked other dogs or hid in the corner, trembling and terrified.

I do not want my little Podengo baby to 'go there'.

[please forgive a newbie if this is against forum protocol....my girl needs help and I'm at a total loss, here]

[Yogi]

Your vet should be the one to tell you the prescribed dosage. Contact your vet for this information. If not, the packaging should provide the information you are looking for.

[Salamander]

Originally Posted by Yogi

Your vet should be the one to tell you the prescribed dosage. Contact your vet for this information. If not, the packaging should provide the information you are looking for.

SO sorry about the breach of forum etiquette, Yogi......

The vet said I had to "find out myself".

I called the company and they can't tell me the dosage, either.

All I know is that she was prescribed ".5 mg once a day".

I'm frantic.

Again, sorry for the link issue.

I only wanted posters to know *what* pills she was being given.

I guess .5 mg of Estriol is .5 mg of Estriol no matter who makes it, really.

I really need help with this or I'm afraid she's going to wind up on Proin.