[CorkyMax]

I found this on the net: Incurin® - Product Details This is suppose to be the name for the veterinarian usage--Incurin. You can check more on the net on this 'wording'
I would make sure that you get the vet worded one (Ask your vet about it).
I would also read this from this site: http://www.ema.europa.eu/docs/en_GB/...C500063389.pdf

Google You have to scroll a little at 1st as the 1st page doesn't hardly show till you get to almost the bottom of it!

I hope these links all come up for you. If not--Put words incurin for dogs in your browser----There are 'tons' of sites to look into----I haven't the time right now as it is time to feed my 2 dogs---Takes longer as I raw feed.

I just clicked on these 3 links in this post and they all worked! But I would still also put the words I mentioned in your browser as it looks like you will find out more, especially as many of the links have comments by other users! Hope this all helps answer your questions.

[Salamander]

Thank you so much, CorkyMax!



Looks like it's a "try it and see" proposition:

Incurin is intended for once daily oral administration.
Since there exists no relation between the final effective dose and the body weight, a fixed dose per kg body weight is not feasible. The dose has to be fixed for each dog on an individual basis. The following dosing schedule is advised: start treatment with 1 tablet every day. If treatment is successful lower the dose to half a tablet a day. If treatment is not successful increase the dose to 2 tablets a day. Some dogs do not need daily treatment; treatment every other day may be tried once the effective daily dose has been established.


Since she's only getting the .5 mg once a day, she's in no danger of weird side effects.
I'll give it to her at that dose and wait a couple weeks to see if it helps.

*Then*, if it doesn't, I'll ask the vet if I should up it to a full mg.

Bless your heart, CM!

[CorkyMax]

You are so welcome! I love dogs and I want to help them all I can. I hope it works at the lowest dosage for your dog. What is your dog's name?

I wanted to say here--Please keep us updated how things are going! You may be able to give some feedback too to other members and guests about this 'sub' for that da*n Proin! Maybe help save another dog's life. Hope it works great for you but if you read this whole long thread---There are other things to try also. Personally if I ever have this problem with my dogs, I will never give Proin no matter what!

[Salamander]

Originally Posted by CorkyMax

You are so welcome! I love dogs and I want to help them all I can. I hope it works at the lowest dosage for your dog. What is your dog's name?

I wanted to say here--Please keep us updated how things are going! You may be able to give some feedback too to other members and guests about this 'sub' for that da*n Proin! Maybe help save another dog's life. Hope it works great for you but if you read this whole long thread---There are other things to try also. Personally if I ever have this problem with my dogs, I will never give Proin no matter what!

Her name is Gypsy and I'd love for you to see her but I can't post links or pics yet.

I read the whole thread last week and kept it bookmarked for when I knew her kidneys were okay to take anything.

This group is a life saver!

I sure will let you know how things are going.

I'm undoubtedly going to need more advice....LOL

[CorkyMax]

It tells you how in the dog forum rules! But here is a pasted message that Yogi had entered a while back: If you scroll down below the post in your "reply" you will see another box.
"additional options". Click on manage attachments and search your computer for the pics you want to download. Finish by scrolling down and clicking on "submit". (You don't need 50 posts first either.)

Leaving you a link here to info on the breed you have. I don't know if there is anything you don't already know--and there are 2 pages of pics to look at also. Just be sure to scroll all the way down the pages as ads get in the middle and can make you think you are at bottom of page when you aren't! And there is a link at bottom of 1st page for the 2nd page of pics. I really like this site as you can look up any breed you want.

Podengo Portugueso Medio Information and Pictures, Medium Portuguese Hound Info

I like the name Gypsy for this breed--It seems to suit her!

[Salamander]

Originally Posted by CorkyMax

It tells you how in the dog forum rules! But here is a pasted message that Yogi had entered a while back: If you scroll down below the post in your "reply" you will see another box.
"additional options". Click on manage attachments and search your computer for the pics you want to download. Finish by scrolling down and clicking on "submit". (You don't need 50 posts first either.)
Leaving you a link here to info on the breed you have. I don't know if there is anything you don't already know--and there are 2 pages of pics to look at also. Just be sure to scroll all the way down the pages as ads get in the middle and can make you think you are at bottom of page when you aren't! And there is a link at bottom of 1st page for the 2nd page of pics. I really like this site as you can look up any breed you want.


I like the name Gypsy for this breed--It seems to suit her!

I tried that and it keeps telling me 'upload failed'.

I think the files are too big.
I'll work on shrinking them down.

She has her own personal page on my website and if the MOD would let me, I could post that, instead.

I named her Gypsy because the Portuguese immigrants in northern CA breed them for rabbit hunting and the ones they don't want, they throw out into the desert, to be eaten by coyotes or perish from lack of food or water.

She and her sister were found and taken to a kill shelter.

The Ibizan Hound rescue found out about them and one member spent the whole day driving them all the way down to a no-kill shelter in southern CA.

I saw their pictures and just couldn't bear to leave them out there.

I started a benefit auction with my own artwork and soon, others contributed their items until we raised enough money to fly Gypsy to Maryland and her sister Darby to Nebraska, where she lives with a wonderful woman who also happens to have the sister of one of my Ibizan Hounds.
[Michelle and I also share the same birthday....imagine that!]....LOL

Considering all the traveling she's done, I thought the name was perfect......

Podengos are even in the movies.

Anyone who's seen "Three Wishes" or "Zeus and Apollo" have seen Medios in starring roles.

Also, the Starburst candy commercial with the dog who has his fanny hanging out of the car window instead of his head is a wire coat Medio.

You can find that on Starburst's YouTube channel.

[he even has his own Facebook page! look for "Huck the Portuguese Podengo"]

Also, I'd bet money that rock star Gene Simmon's dog "Snippy" is a Medio.

Sometimes, you accidentally find something you never knew you were looking for and discover that now, you can't imagine life without it.

That's how I feel about my little velociraptor, Gypsy....LOL

[she really does run all the other much bigger dogs].....

[Salamander]

UPDATE!

Gypsy got her Estriol caps last week and she's already down to maybe one or two very small damp spots per day, already!

No more waking up in soaking puddles for my baby!

Thanks SO much to everybody here!

[CorkyMax]

I am so happy that this different thing is working so well! Please keep us updated--Maybe will encourage other people to try it!

Gee, maybe I spoke too soon----Is this 'med' as safe as we want it to be? Has to be better then Proin but how safe is it? Any side effects or warnings given on it? I would check it out myself but things are kind of hectic for me right now!

[Salamander]

Originally Posted by CorkyMax

I am so happy that this different thing is working so well! Please keep us updated--Maybe will encourage other people to try it!

Gee, maybe I spoke too soon----Is this 'med' as safe as we want it to be? Has to be better then Proin but how safe is it? Any side effects or warnings given on it? I would check it out myself but things are kind of hectic for me right now!

Totally, totally safe!
Beneficial, in fact.

If you give "too much", the bitch will just get enlarged teats/vulva and become 'attractive' to male dogs.

If that happens, cut the dose, problem solved.

It does NOT cause bone marrow failure like the other estrogen replacements.

It actually enhances bone density and prevents mammary tumors.

It's all good with no dangerous side effects.

She's also much cheerier than she's been ever since she was spayed.

When you consider that spaying a dog throws them into instant 'menopause', it's affecting every other part of their endocrine system, just as it does a human female.

Estriol puts back part of what got taken away.

She feels great again!

Personally, I'm just over-joyed.

[CorkyMax]

Sorry to be such a 'dummy!' Here I had posted about this before to you and totally forgot about it--I generally go back and read a few previous posts in the thread (replies I had made 1st!) My only excuse is that I have been so 'involved' since Yogi died and just have not been as focused on answering posts lately. You prob. know about Yogi from the thread I started to let people know about his death.

But I am glad to read your last post and a lot of others will be too. Wouldn't it be great to get Proin off the market and vets start prescribing Estriol in place of it. This is the name for the human med but I think I read that Incurin is the name for it for dog/vet usuage.

And very happy that you checked out things before giving that Proin---Gypsy is a very lucky dog to have you as a parent. And to think she is so happy now! What an awful difference that da*n Proin could/would of made!!

[Salamander]

OMG!

I did not know Yogi had passed away!

I am SO sorry!!!

This has been a hectic week, what with all the new dog meds being 'tested' on my kids and I simply haven't had time to check up on my online "life".

My condolences to his family, his fur kids and everyone here.

[CorkyMax]

Yes it is sad about Yogi. Here is a thread you may of missed about him: Very Sad News!!! Please read!

[HeatherA]

My 8 year old Rat Terrier was just prescribed PPA after years of urinating in her sleep. After a UTI check she was put on this yesterday. I gave her the proper dosage last night and today, a normal hyperactive terrier is acting like a 13 year old basset hound. She is just sleeping all day, walks around really slow with her eyes kinda glazed over. I called my vet and they said its probably not related to the medication and to just watch her (but take her off the meds). Im thinking im not giving her that ever again.

[CorkyMax]

So very glad you took your dog (name?) off that killer! Count yourself very lucky (and your dog too!) that one (2) pill didn't do her in! I hate to tell you this but there could still be problems and hopefully it hasn't damaged the kidneys/liver, etc. I wonder if blood tests should be done to make sure. And that is another thing--I hope your vet did blood work before prescribing this crap!!??? If he/she didn't--I would be looking for another vet!!
And if he did do blood work---I wonder what blood work done now would prove about this crap (I hate the crap so much I don't even want to use the word proin!)

I suggest you read this entire long thread to see what I mean about your dog may not be 'out of the woods' yet and also there are a lot of safer alternatives to try that are mentioned in some of the posts in this thread. If she is just doing this as she sleeps at night--You could put a diaper on her at night if nothing else works!!

Please keep us informed as to how your dog is doing or we will be worrying about what is happening to her! Hope you stopped it in time and no more ill effects. I know things cost money but if it was my dog I'd be worried about what it may of done to kidney function and for peace of mind I think I'd get blood tests! If damage was found I am not sure if it can be fixed? Sorry to add to your worries but I want your dog to stay healthy---hoping for the best for her!!

[B]Quote from your post: I called my vet and they said its probably not related to the medication and to just watch her (but take her off the meds). I am so sick of hearing vets say things like that esp. about proin!!! Are they so 'conditioned' to what the pharmaceutical companies, etc. tell them---Are they brainwashed or what!!! How can they not know what this proin does to dogs----It was causing strokes in women and was banned for human use--Da*n greedy pharmaceutical companies have to make their money off of it somehow--so our innocent sweet dogs are once again scape goats!!

[HeatherA]

Luckily I only gave her one dose of the medicine before she had a side effect. The extreme drowsiness was luckily VERY obvious in a normally hyper dog, so I immediately did some research on the drug. I agree with the vet that Lethargy is not a usual side effect of the drug, but after reading other peoples concerns any obviouse side effect like that is not worth the risk. Today she is back to her normal self so I am 100% sure it was the medicine. I wonder if the vet will give me a refund on the pills since I only used one!? She is a healthy girl and just has trouble with urinating in her sleep. it is aggrevating having to constantly clean her bedding and cleaning her after sleeping in it... but Id rather have a little aggrevation than not have her. I am going to talk about other options, maybe try some of the more natual remedys listed here. And see maybe if a doggy diaper might work. Im not sure if she would keep a diaper on though... she is pretty bad about chewing things up like that. so we shall see. If nothing else I will just buy some old towels and keep a laundry basket in the garage for her bedding and that way I can just do laundry once a week rather than every day. May have to say goodbye to the nice fluffy bedding she is used to. Just glad I read all this before it was too late. P.S. I called the vet again just now and told them she was better today.... tey told me to try giving her the pill again to see if it gave the same result as yesterday to really for sure rule out it was the pills! ummm I said.. yeah thanks but no thanks. Im not taking that risk. If nothing else if it just made her lethargic and nothing else... I didnt like seeing my dog like that. Its not real living it she just sleeps all day and looks pitiful. She is going to call me back to see if I can get a refund no the pills. She had to ask the Vet.

[Salamander]

It's all very simple, deductive reasoning, actually.

If it was BANNED for human use due to deadly side effects, why would we want to give it to our pets?

Remember the "wonder drug" Celebrex?

It was a COX2-Enzyme inhibitor.

It killed people and was banned.

Now your vet is giving the very same banned chemical to your dog but it's called Rimadyl, instead.
[I lost my sweet Izzy to Rimadyl]

When they figured out that pet owners were wise to the Rimadyl scam, they simply gave it another name.

I had a vet tell me the pain meds he was trying give my dog were not Cox2 EI but then I pointed to the HUGE advertising poster right behind me giving the drug's chemical name.

It was a COX2 EI.
[those meds always end in the suffix "-coxin"]

So, no PROIN....ever.
[ad yes, I've had a lot of people say their dog took it for years with no bad side effects...but I'm not going to gamble with my dog's life]

I've heard people say they've had great results with corn silk.

I've had to take Gypsy off the wonderfully effective Estriol because it made her smell 'attractive' to my intact male Dobe and he's not eating, as is normal behavior for "distracted males".

We'll be trying corn silk, next.

The short amount of time she was on Estriol, however, radically reduced her leakage and benefited her generally, overall.

If you have no intact males in your house, it's what I'd recommend.

Good luck!

[CorkyMax]

Here is a hint for those of you that have tried using subs for the killer, proin, and have decided to go with diapers: Consider using disposable diapers. If you don't want to spend extra money on pet diapers, use a pair of scissors to cut a small opening for the pet's tail about 1 inch below the waistline of the front of the diaper. Using masking tape, cover the edges of the cut opening to prevent seepage. Secure the disposable diaper on the pet backward for a better fit.