Do discuss it with your vet; discussing alone won't hurt anything, but is very prudent. A competent vet will refuse to vaccinate any animal that is considered too sick to withstand it. For example, one year I took both my puppy and my elderly cat in for annual exams and shots. Upon examining my cat, the vet noticed he was jaundiced and perhaps anemic, and said he could not in good conscience vaccinate him. Instead, he ordered blood work. The blood work revealed my cat to be suffering from liver disease. So for the last two years of my cat's life, he was unable to be vaccinated.
So... discuss it with your vet, and together decide whether he and you both feel your dog is healthy enough to tolerate the vaccine and/or the heartworm treatments. In these types of cases, one must always weigh the benefits against the risks.... kind of like a pregnant woman taking medications for a life-threatening condition, versus the health of the unborn baby. One other possibility is to ask for a titer test on the distemper-- if his titer levels show sufficient immunity to the distemper, then the vaccine can definitely be safely omitted, in good conscience.
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